Gout

发表于: 03/07/2025

What Is Gout?

Gout is a type of arthritis that leads to sudden, severe joint pain and swelling. It happens when uric acid crystals build up in the joints, causing inflammation. This condition tends to affect men more often and is commonly linked to obesity, hypertension, and diabetes.

A gout flare can begin without warning and is usually marked by intense pain in one or more joints. While it can affect any joint, gout most often impacts the big toe, but can also affect the ankles, knees, fingers, wrists, elbows, and the midfoot.

Common Symptoms of Gout

Recognisable signs of a gout attack include:

  • Sharp, intense joint pain
  • Redness and warmth in the affected area
  • Swelling and tenderness
  • Joint stiffness

Symptoms tend to appear suddenly and may last anywhere from 3 to 10 days. Without proper management, recurring attacks are frequent and can happen within months of the initial episode.

Risk Factors That Increase Gout Risk

Gout is primarily caused by high levels of uric acid in the blood (hyperuricemia). Several factors can contribute to this, such as:

  1. Diet:
    Regular intake of red meat, seafood, sugary drinks, and excessive alcohol can increase uric acid production.
  2. Age & Gender:
    Men between 30 and 45 are more susceptible. Post-menopausal women and individuals over 65 also face an elevated risk.
  3. Medical Conditions:
    Conditions like high blood pressure, obesity, type 2 diabetes, and chronic kidney disease can raise the chances of developing gout.
  4. Medications:
    Certain medications, such as diuretics, may increase uric acid levels in the body.

How Is Gout Diagnosed?

If you experience sudden joint pain that comes and goes and have persistently high uric acid levels, gout may be the likely cause.

Diagnosis involves a review of your medical history, physical examination, and diagnostic testing, which may include:

Synovial Fluid Analysis:
A small amount of fluid is taken from the affected joint and examined under a microscope for urate crystals.

Tophus Analysis:
If you have visible tophi (lumps under the skin), a needle biopsy can help confirm the presence of uric acid deposits.

Blood Test (Uric Acid Level):
This checks the concentration of uric acid in your blood or urine. Elevated levels suggest a possible gout diagnosis.

Gout Treatment Options
The goal of treatment is to reduce pain quickly and prevent future flare-ups. Depending on the severity and frequency of your symptoms, your doctor may recommend:

Medications

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Ibuprofen, naproxen, or indomethacin help relieve inflammation.
  • Colchicine: Especially effective during the early stages of a flare.
  • Corticosteroids: These can be prescribed when NSAIDs or colchicine are unsuitable.

Urate-Lowering Therapy (ULT)

For those with recurring attacks or complications, long-term medications such as allopurinol or febuxostat can help lower uric acid levels in the body.

Lifestyle Modifications for Gout Management

Adopting healthier habits can reduce your risk of future attacks:

  • Maintain a healthy weight
  • Exercise regularly
  • Limit or avoid red meat, oily fish, and yeast-rich products
  • Cut down on sugary drinks and alcohol
  • Stay hydrated by drinking plenty of water

Potential Complications if Gout Is Untreated

Ignoring gout can lead to serious health issues over time, including:

  • Permanent joint damage or deformity
  • Chronic arthritis (gouty arthritis)
  • Formation of tophi — hard lumps of uric acid under the skin
  • Kidney problems, including kidney stones or damage
  • Higher risk of heart disease

Timely diagnosis and treatment are crucial in preventing these complications and improving your overall quality of life.

Conclusion

Gout is more than just a painful joint condition—it can affect your daily life and long-term health if not managed properly. Speak to a healthcare professional if you suspect you have gout or are at risk. Early intervention, proper medication, and lifestyle changes can make a significant difference in controlling this condition.


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