A Multicenter, Retrospective, Noninterventional Study to Determine the Prevalence of HER2-low, Clinical Characteristics, Treatment Patterns, and Associated Outcomes in Patients Previously Identified With HER2-negative Locally-advanced or Metastatic Breast Cancer Who Progressed on Systemic Anticancer Therapy
Status
Active (Non-Recruiting)
Disease
HER2-negative breast cancer
Treament Agent
N/A
Study Phase
Retrospective
Resources and Links
Physician Name(s)
Dr Mastura Md Yusof
Dr Sarala Ravindran
Dr Malwinder Singh Sandhu
Description
This non-interventional, multicenter, retrospective study aims to estimate the prevalence, characteristics, treatment patterns, and outcomes of HER2-low metastatic breast cancer (mBC) by re-examining archived FFPE slides in patients previously classified as HER2-negative. The study includes patients from regions with limited data on HER2-low mBC, focusing on those with HER2-negative, locally advanced or metastatic disease who progressed on systemic therapies between January 2019 and December 2022, with at least 12 months of follow-up data. HR-positive patients who progressed within 24 months after adjuvant endocrine therapy are also eligible.
Cancer Type
Breast Cancer
I would like to be a part of tomorrow's breakthrough
Clinical trials are part of research studies involving patient volunteers that are conducted to find safe and effective treatments for a variety of health conditions. They are critical to the advancement of medicine and improving patient health. Participating in clinical trials offers patients the opportunity to try new and effective treatments that could potentially improve their condition while taking part in vital research that can benefit many future patients.
In Pantai Hospital Kuala Lumpur, clinical trials are carried out under our Clinical Research team.
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