Research Publications

Clinical and demographic pattern of chronic granulomatous disease (CGD) from a multicenter perspective: Malaysia’s experience over 26 years

A retrospective review of clinical manifestations and demographic pattern of patients diagnosed as chronic granulomatous disease (CGD) from 7 hospitals in Malaysia. An analysis of the available database would establish clinical characteristics, diagnoses and outcome including microbiologic pattern. Studying the demography allows us to document the occurrence of CGD amongst multiethnic groups and its geographical distribution for Malaysia.

Allergy, Asthma and Immunology 2021
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Real-world multicenter study of the safety and efficacy of netupitant plus palonosetron fixed-dose combination to prevent chemotherapy-induced nausea and vomiting among Malaysian patients receiving moderately or highly emetogenic chemotherapy

Asia-Pacific Journal of Clinical Oncology 2021
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Socialization During the COVID-19 Pandemic: The Role of Social and Scientific Networks During Social Distancing

Advances in Experimental Medicine and Biology 2021
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Strategies and Future Opportunities for the Prevention, Diagnosis, and Management of Cow Milk Allergy

Real-world multicenter study of the safety and efficacy of netupitant plus palonosetron fixed-dose combination to prevent chemotherapy-induced nausea and vomiting among Malaysian patients receiving moderately or highly emetogenic chemotherapy

Advances in Experimental Medicine and Biology 2021
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Asia Pacific Association of Allergy Asthma and Clinical Immunology White Paper 2020 on climate change, air pollution, and biodiversity in Asia-Pacific and impact on allergic diseases

Asia Pacific Allergy 2020
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Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific

The Asia Pacific Society for Immunodeficiencies (APSID) conducted nine primary immunodeficiency (PID) Schools in 5 years since inauguration to provide PID care training for early career physicians in Asia Pacific, a region with divergent needs in PID resources and training.

Frontiers in Immunology 2020
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Diagnostic procedures & practices in drug allergy/hypersensitivity: a survey of 13 Asian countries

The issues and challenges in the diagnosis of drug allergy/hypersensitivity among children and adults in Asia are likely to be different from non-Asian countries.

Asia Pacific Allergy 2020
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Drug hypersensitivity reactions in Asia: regional issues and challenges

Asia Pacific Allergy 2020
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KEYNOTE-355: Randomised, Double-Blind, Phase III Study of Pembrolizumab + Chemotherapy versus Placebo + Chemotherapy for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple-Negative Breast Cancer

Pembrolizumab monotherapy showed durable antitumour activity and manageable safety in patients with metastatic triple-negative breast cancer. We aimed to examine whether the addition of pembrolizumab would enhance the antitumour activity of chemotherapy in patients with metastatic triple-negative breast cancer.

Journal of Clinical Oncology 2020
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Pan-Asian Adapted ESMO Clinical Practice Guidelines for the Management of Patients with Early Breast Cancer: A KSMO-ESMO Initiative Endorsed by CSCO, ISMPO, JSMO, MOS, SSO and TOS

Annals of Oncology 2020
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Partially hydrolyzed formula in non-exclusively breastfed infants: A systematic review and expert consensus

Nutrition 2019
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Real-World Experience of First-Line Afatinib in Patients with EGFR-Mutant Advanced NSCLC: A Multicenter Observational Study

This study aimed to evaluate the efficacy, side-effects and resistance mechanisms of first-line afatinib in a real-world setting.

BMC Cancer 2019
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Pan-Asian Adapted ESMO Consensus Guidelines for the Management of Patients With Metastatic Colorectal Cancer: A JSMO-ESMO Initiative Endorsed by CSCO, KACO, MOS, SSO and TOS

Annals of Oncology 2018
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The Efficacy and Tolerability of Scalp Cooling in Preventing Chemotherapy-Induced Alopecia in Patients with Breast Cancer Receiving Anthracycline and Taxane-Based Chemotherapy in an Asian Setting

Scalp cooling has been shown in several studies to be an effective method in preventing chemotherapy-induced alopecia (CIA). Data on the use of scalp cooling in Asian countries are limited, and evidence for its use and efficacy among our patients are not available.

Indian Journal of Cancer 2018
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Impact of Cancer on Employment: A Qualitative Study Exploring Employment Changes and Financial Coping Strategies Following Breast Cancer

Few studies have examined the impact of cancer diagnosis on employment among breastcancer patients. We aim to gain an in-depth understanding on the employment issues faced by breast cancer patients aswell as their financial coping strategies in a multi-ethnic Asian setting.

Advances in Modern Oncology Research 2017
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Ethnicity influences disease characteristics and symptom severity in allergic rhinitis patients in Malaysia

The number of available reports regarding the influence of ethnicity on clinical features of allergic rhinitis (AR), especially disease severity in tropical climates, is limited. We aimed to compare clinical parameters and disease severity in AR patients of different ethnicities.

International Forum of Allergy and Rhinology 2016
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Safety and Management of Toxicity Related to Aflibercept in Combination with Fluorouracil, Leucovorin and Irinotecan in Malaysian Patients with Metastatic Colorectal Cancer

Between October 2012 and February 2015, 25 patients with metastatic colorectal cancer (mCRC) (mean age, 57.0 ± 12.1 years) were granted access to aflibercept via the Aflibercept Named Patient Program at four centers.

Asian Pacific Journal of Cancer Prevention 2015
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Clinical trials are part of research studies involving patient volunteers that are conducted to find safe and effective treatments for a variety of health conditions. They are critical to the advancement of medicine and improving patient health. Participating in clinical trials offers patients the opportunity to try new and effective treatments that could potentially improve their condition while taking part in vital research that can benefit many future patients.

In Pantai Hospital Kuala Lumpur, clinical trials are carried out under our Clinical Research team.

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