A Randomized, Multicenter, Phase 3 Study of Zanidatamab in Combination with Chemotherapy with or without Tislelizumab in Subjects with HER2-positive Unresectable Locally Advanced or Metastatic Gastroesophageal Adenocarcinoma (GEA)

Status

Closed

Disease

Gastroesophageal Adenocarcinoma

Treament Agent

Trastuzumab + CAPOX or 5-FU vs Zanidatamab + CAPOX or 5-FU vs Zanidatamb + Tislelizumab CAPOX or 5-FU

Study Phase

III

Resources and Links

clinicaltrials.gov NCT05152147

Physician Name(s)

Datuk Dr Lam Kai Seng

Dr Malwinder Singh Sandhu

Dr A.B. Manivannan

Description

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzumab given with chemotherapy.

Cancer Type

Gastroesophageal Cancer

I would like to be a part of tomorrow's breakthrough

Clinical trials are part of research studies involving patient volunteers that are conducted to find safe and effective treatments for a variety of health conditions. They are critical to the advancement of medicine and improving patient health. Participating in clinical trials offers patients the opportunity to try new and effective treatments that could potentially improve their condition while taking part in vital research that can benefit many future patients.

In Pantai Hospital Kuala Lumpur, clinical trials are carried out under our Clinical Research team.

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