Coronary Artery Disease (CAD)
What is coronary artery disease?
Coronary artery disease (CAD), also known as
coronary heart disease (CHD) or ischaemic heart
disease, occurs when your body’s major blood vessels
that supply the heart struggle to send enough blood,
oxygen, and nutrients to the heart muscle.
What are the causes of coronary artery disease?
CAD is commonly caused by inflammation of the
arteries, which is the result of arterial plaque
build-up. Plaque contains deposits of cholesterol
and other substances in the artery. When the
arteries narrow over time due to plaque build-up,
the blood flow can be partially or totally blocked.
This process is called atherosclerosis.
What are the symptoms of coronary artery disease?
- Chest pain or pressure: Pain in the chest
(also called angina) as well as pressure or the
sensation of tightness, occasionally may extend
to the neck, arm or back.
- Weakness
- Dizziness
- Shortness of breath and fatigue
- Heart attack: Classic signs of a heart
attack include chest pain, shoulder or arm pain,
shortness of breath and sweating
Symptoms may not manifest in the early stages as it
may take anywhere from years to decades for plaque
build-up.
What are the risk factors of coronary artery
disease?
- Unhealthy diet: Diet rich in saturated
fat, trans fat, sugar, and salt
- Family history: Having a close relative
who developed heart disease at an early age, or
family history of heart disease
- Diabetes
- Gender: Men are at greater risk of
developing CAD, while the risk for women
increases after menopause
- Overweight or obesity
- Older age
- Hypertension
- High cholesterol
How is coronary artery disease diagnosed?
Other than a physical examination, your cardiologist
may require you to take one or more of the following
tests:
- Electrocardiograph tests (EKG)
- Exercise stress tests/ treadmill tests (TMT)
- Pharmacological stress test
- Echocardiogram
- Blood tests (to measure cholesterol,
triglycerides, C-reactive protein, glucose,
HbA1c, etc.)
- Cardiac catheterisation
- Coronary calcium scan
- Nuclear imaging
- Computed tomography angiogram
What are the treatment options for coronary artery
disease?
- Medications: Heart-related medicines
e.g., medicines to lower cholesterol levels and
blood pressure, medicines to manage angina, and
anticoagulants and antiplatelet to reduce blood
clots
- Non-surgical treatments: e.g., balloon
angioplasty and stenting
- Surgical interventions:e.g., coronary
artery bypass graft surgery (CABG)
What are the prevention tips for coronary artery
disease?
Consider making the following lifestyle changes:
- Stop smoking or avoid getting into the habit of
smoking
- Make dietary changes to manage health issues
such as cholesterol and blood pressure
- Maintain a healthy weight
- Reduce and manage stress
- Limit the consumption of alcohol
- Exercise and increase your physical activity
level
References
- Coronary artery disease (CAD). Available at
https://www.cdc.gov/heartdisease/coronary_ad.htm
[Accessed on 29 April 2022]
- Coronary artery disease. Available at
https://www.mayoclinic.org/diseases-conditions/coronary-artery-disease/symptoms-causes/syc-20350613?p=1
[Accessed on 29 April 2022]
- Coronary artery disease. Available at
https://my.clevelandclinic.org/health/diseases/16898-coronary-artery-disease
[Accessed on 29 April 2022]