HPV Test vs. Pap Test: What's the Difference?

Diterbitkan pada: 29/07/2025

Cervical cancer screening is essential for early detection and prevention, but many people are confused about the differences between an HPV test and a Pap test. These tests, while complementary, serve distinct purposes:

HPV Test: Detects high-risk types of the human papillomavirus (HPV), which are associated with cervical cancer. This test focuses on identifying the virus itself, even before cellular changes occur.

Pap Test (Pap Smear): Examines cervical cells for abnormalities that could indicate precancerous changes or cervical cancer. It does not directly test for HPV but detects changes caused by the virus.

Both tests are crucial tools for protecting cervical health, often used together in co-testing protocols. However, individual recommendations vary based on age, medical history, and risk factors. According to (National Institute of Health) NIH, the population-level, organised screening programs have reduced cervical cancer rates by 50% to 80% (NIH, 2020). At Pantai Hospitals you can get screening services by trained professionals and the latest screening technology and methods. 

What Are the Main Causes of Human Papillomavirus and Cervical Cancer?

Cervical cancer is primarily linked to persistent infection with high-risk types of HPV. Understanding the causes of HPV and cervical cancer can help in prevention

  • HPV Transmission:

    • HPV is a sexually transmitted infection (STI) spread through skin-to-skin contact during sexual activity.
    • Certain behaviours, such as having multiple sexual partners or unprotected intercourse, increase the risk of contracting HPV.
  • Risk Factors for Cervical Cancer:

    • Persistent high-risk HPV infection.
    • Weakened immune system (e.g., due to HIV).
    • Smoking, which damages cervical cells and weakens the body's ability to fight infections.
    • Long-term use of oral contraceptives and other factors such as early sexual activity.

The World Health Organization (WHO) reports that HPV types 16 and 18 are responsible for approximately 70% of cervical cancer cases worldwide (WHO, 2020).

What are the Benefits for HPV and Pap Test ?

HPV Test Benefits:

  • Early Detection of High-Risk HPV: Identifies the virus before cellular abnormalities appear.
  • Prolonged Screening Intervals: For women aged 30 and above, a negative HPV test may allow for longer intervals between screenings.
  • Targeted Prevention: Helps identify those at higher risk, prompting closer monitoring or preventive interventions.

Pap Test Benefits:

  • Identifies Cellular Changes: Detects early-stage abnormal cells that may develop into cancer if untreated.
  • Proven Track Record: Decades of use have demonstrated its effectiveness in reducing cervical cancer incidence and mortality.
  • Guides Treatment Decisions: Helps determine whether additional diagnostic procedures, such as a colposcopy, are needed.

Both tests are most effective when used as part of a routine screening schedule recommended by healthcare providers. According to the American Cancer Society, combining these tests (co-testing) significantly increases the accuracy of cervical cancer screening (ACS, 2022).

Will It Affect My Fertility Health?

Many individuals worry that cervical cancer screenings or treatments might influence their ability to conceive. It is essential to address these concerns with accurate information, particularly for those seeking advice from a fertility clinic in Malaysia.

The HPV test and Pap test are straightforward, non-invasive procedures that involve collecting cervical cell samples. These tests themselves have no impact on fertility, making them safe for women planning pregnancies. The concerns about fertility usually arise when follow-up treatments are required due to abnormal results.

For instance, treatments such as cryotherapy, laser therapy, or cone biopsy are often used to manage precancerous or cancerous cervical cells. While these procedures are effective, some may slightly increase the risk of complications like cervical incompetence or preterm labour. However, advancements in medical techniques have greatly minimised such risks. 

If you have concerns about how these procedures might affect your reproductive health, consulting with a fertility clinic in Malaysia can provide tailored guidance. Specialists can help you understand the risks and benefits, ensuring that your health and fertility goals align with your treatment choices. Open communication with your healthcare provider is key to addressing any fertility-related concerns effectively.

Book an Appointment at Pantai Hospital Penang

Understanding the differences between HPV and Pap tests, their benefits, and their potential impact on fertility is vital for making informed health choices. Regular screenings, combined with lifestyle adjustments and vaccination, can dramatically reduce the risk of cervical cancer. For those seeking expert advice or wishing to take proactive steps for their health, Pantai Hospital Penang offers comprehensive screening services. Book an appointment today to receive personalised care from their dedicated team of specialists, ensuring your health is in the best hands. You may also book an appointment by downloading the MyHealth360 application from the Google Play Store orApple App Store.

Pantai Hospitals have been accredited by the Malaysian Society for Quality in Health (MSQH) for its commitment to patient safety and service quality. Do not let the condition progress. 


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